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Oxymorphone works by attaching to nerve receptors in the brain and increasing the body’s threshold to pain. It also changes the way the pain is experienced and perceived. When abused, it creates intense feelings of euphoria and relaxation, as well as pain relief.

Oxymorphone was sold under the brand name Opana, but in June of 2017, the FDA asked the manufacturer to remove it from the U.S. market due to high rates of abuse and the ongoing opioid epidemic in America. Opana ER was removed from the U.S. market in July of 2017, but doctors may still legally prescribe generic versions of extended-release oxymorphone tablets in the U.S.

How Common Is Opana (Oxymorphone) Addiction?

Oxymorphone has a high potential for abuse and addiction because it is a very powerful drug. According to the Substance Abuse and Mental Health Services Administration’s (SAMHSA) 2016 National Survey on Drug Use and Health, 18.7 million people (or 6.9 percent of the population) misused prescription drugs like oxymorphone.

Many people may begin using oxymorphone without intending to abuse it, taking it as prescribed by a doctor. But regular use can lead to tolerance, which will make a person feel like they need more of the drug to feel the same effects. As tolerance develops, the risk for Opana addiction increases, and is much more likely to occur.

Physiological and psychological dependence is not uncommon with oxymorphone and anyone who has developed a tolerance or is misusing it should seek professional help immediately.